Zelapar Dosage

Your healthcare provider will consider several factors when determining the best Zelapar dosage for you. This includes things such as how you respond to Zelapar, other medications you are taking, and other medical conditions you have. The recommended starting dose is Zelapar 1.25 mg, taken once daily in the morning before breakfast. In no situation should the Zelapar dosage exceed 2.5 mg per day.

 

Zelapar Dosage: An Introduction

The dose of Zelapar® (orally disintegrating selegiline) your healthcare provider recommends will vary, depending on a number of factors, including:
 
  • How you respond to Zelapar
  • Other medications you are taking
  • Other medical conditions you may have.
     
As is always the case, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
 

Zelapar Dosage for Parkinson's Disease

The recommended starting Zelapar dosage for Parkinson's disease is Zelapar 1.25 mg, taken once daily in the morning before breakfast. After at least six weeks, if necessary, your healthcare provider may increase your dose up to Zelapar 2.5 mg (two 1.25-mg tablets), taken once daily in the morning before breakfast. In no case should the dose be increased to more than 2.5 mg per day.
 
Zelapar is approved for use in combination with levodopa-carbidopa medications, such as Sinemet®, Sinemet CR, or Parcopa®. Many people will need to use a lower carbidopa-levodopa dosage, especially if side effects occur. Your healthcare provider will determine when and if you need to lower your carbidopa-levodopa dosage.
 
Because the liver and kidneys help remove Zelapar from the body, people with liver or kidney problems may need a lower Zelapar dosage, although specific recommendations are not available.
 
(Zelapar Dosage Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;