Tasmar is used for treating symptoms of Parkinson's disease in adults. It is used in conjunction with carbidopa-levodopa products, as it is not effective at treating Parkinson's disease when used alone. Adding Tasmar to carbidopa-levodopa has been shown to decrease the times when the medication does not work well and increase times when it does. There are currently no universally accepted off-label Tasmar uses.
Tasmar Uses: An OverviewTasmar® (tolcapone) is a prescription Parkinson's disease medication. It is approved for use in combination with carbidopa-levodopa products (Sinemet®, Sinemet CR, or Parcopa®). The medication is specifically designed for people who are experiencing carbidopa-levodopa fluctuation symptoms, such as "wearing-off" (when the medication stops working before the next dose). Although studies have shown that people who do not have fluctuation symptoms may benefit from Tasmar, the risks of this medication (especially liver failure) outweigh the possible benefits for such people.
What Is Parkinson's Disease?Parkinson's disease is a progressive neurological disease that results from the loss of neurons in a region of the brain that controls movement. This creates a shortage of dopamine, an important brain-signaling chemical (neurotransmitter), causing the movement problems characteristic of Parkinson's disease. The exact cause of Parkinson's disease is not currently known.
Although early symptoms of Parkinson's disease may be subtle, people will eventually develop a characteristic tremor (shaking or trembling), typically when the body is at rest. As the disease progresses, symptoms may worsen and new ones may appear.
Depending on the severity of a person's symptoms, Parkinson's disease treatment can include:
- Medications (see Medications for Parkinson's Disease)
- Lifestyle changes and support.