Stalevo Side Effects

Involuntary body movements, urine discoloration, and nausea are some of the common side effects reported with Stalevo. Reactions to this drug are generally minor, but many people will begin to experience significant and sometimes intolerable side effects over time. Potentially serious side effects that should be reported to your healthcare provider immediately include fainting, severe diarrhea, seizures, and psychiatric problems.

An Introduction to Stalevo Side Effects

As with any medicine, side effects are possible with Stalevo® (carbidopa-levodopa-entacapone). If side effects do occur, they are often minor and either require no treatment or can be treated easily by you or your healthcare provider. However, as with any levodopa therapy, many people begin to experience significant and sometimes intolerable Stalevo side effects over time.
 
(This article covers many, but not all, of the possible side effects with Stalevo. Your healthcare provider can discuss a more complete list with you.)
 

Common Side Effects of Stalevo

Stalevo has been studied thoroughly in clinical trials. In these studies, the side effects that occurred in a group of people taking Stalevo were documented and compared to side effects that occurred in another group of people taking just carbidopa-levodopa (without the entacapone). This way, it was possible to see what side effects occurred, how often they appeared, and how they compared to the group taking just carbidopa-levodopa.
 
In these studies, the most common Stalevo side effects included:
 
  • Involuntary body movements (dyskinesia) -- in up to 25 percent of people
  • Nausea -- up to 14 percent
  • Diarrhea -- up to 10 percent
  • Urine discoloration -- up to 10 percent
  • Excessive muscle movements (hyperkinesia) -- up to 10 percent
  • Slow or diminished muscle movements (hypokinesia) -- up to 9 percent
  • Dizziness -- up to 8 percent
  • Abdominal pain (stomach pain) -- up to 8 percent.
     
Other common side effects (occurring in 1 to 6 percent of people) included:
 
  • Increased sweating
  • Back pain
  • Taste changes
  • Constipation
  • Vomiting
  • Dry mouth
  • Indigestion or heartburn
  • Gas
  • Red or purple bruise-like spots (known as purpura)
  • Fatigue
  • Weakness
  • Bacterial infection.
     
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Stalevo Drug Information

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