Parkinsons Disease Channel
Topics & Medications
Quicklinks
Related Channels
Stalevo Drug Interactions
When certain medications, such as antipsychotics or blood pressure medicines, are taken with Stalevo, drug interactions may occur. Some interactions can make Stalevo less effective, while others can increase the risk of dangerous side effects. Tell your healthcare provider about all other medications you are taking before starting Parkinson's treatment. Other medications that may cause Stalevo drug interactions include cholestyramine, probenecid, and tricyclic antidepressants.
Stalevo® (carbidopa-levodopa-entacapone) can potentially interact with several different medications. Some of the medicines that may lead to Stalevo drug interactions include:
- Antipsychotic medications
- Blood pressure medications
- Certain antibiotics, such as:
- Ampicillin
- Chloramphenicol
- Erythromycin (Ery-Tab®)
- Rifampicin (Rifadin®)
- Cholestyramine (Prevalite®, Questran®, Questran® Light)
- Iron
- Isoniazid
- Medications metabolized by catechol-O-methyltransferase (COMT), such as:
- Apomorphine (Apokyn®)
- Dobutamine
- Dopamine
- Epinephrine (Adrenalin®, EpiPen®, Primatene® Mist)
- Isoproterenol (Isuprel®)
- Methyldopa
- Norepinephrine (Levophed®)
- Metoclopramide (Reglan®)
- Monoamine oxidase inhibitors (MAOIs), such as:
- Isocarboxazid (Marplan®)
- Phenelzine (Nardil®)
- Rasagiline (Azilect®)
- Selegiline (Eldepryl®, Emsam®, Zelapar®)
- Tranylcypromine (Parnate®)
- Phenytoin (Dilantin®, Phenytek®)
- Probenecid
- Tricyclic antidepressants, such as:
- Amitriptyline (Elavil®)
- Amoxapine (Asendin®)
- Clomipramine (Anafranil®)
- Desipramine (Norpramin®)
- Doxepin (Sinequan®, Silenor®)
- Imipramine (Tofranil®, Tofranil PM®)
- Maprotiline (Ludiomil®)
- Nortriptyline (Pamelor®)
- Protriptyline (Vivactil®)
- Trimipramine (Surmontil®).
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD