Before taking Sinemet, warnings and precautions should be reviewed with your healthcare provider. For example, Sinemet can make certain health conditions worse, such as malignant melanoma and certain mental illnesses. Tell your healthcare provider about any medical conditions you have and any other medications you are taking before starting Sinemet. Warnings and precautions also extend to women who are pregnant or breastfeeding.
Kidney disease, such as kidney failure (renal failure)
Liver disease, such as liver failure, cirrhosis, or hepatitis
A history of stomach or intestinal ulcers
Any allergies, including allergies to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
Pregnant or thinking of becoming pregnant
Breastfeeding.
Make sure to tell your healthcare provider about any medications you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.