Drug InteractionsSinemet can potentially interact with a number of other medicines (see Sinemet Drug Interactions).
What Should I Tell My Healthcare Provider?Talk with your healthcare provider prior to taking Sinemet if you have:
- Malignant melanoma (a type of skin cancer) or any undiagnosed skin lesions
- Glaucoma (an eye condition)
- Any mental illness, including depression
- Heart problems of any kind
- Lung problems, such as asthma or chronic obstructive pulmonary disease (COPD)
- Kidney disease, such as kidney failure (renal failure)
- Liver disease, such as liver failure, cirrhosis, or hepatitis
- A history of stomach or intestinal ulcers
- Any allergies, including allergies to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
- Pregnant or thinking of becoming pregnant (see Sinemet and Pregnancy)
- Breastfeeding (see Sinemet and Breastfeeding).
Make sure to tell your healthcare provider about any other medications you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
(Click Sinemet Warnings and Precautions to learn more, including information on who should not take the drug.)
- Confusion or agitation
- Insomnia and restlessness
- Involuntary body movements
- Nausea and vomiting
- A rapid heart rate (tachycardia)
- Low blood pressure (hypotension) or high blood pressure (hypertension).
If you happen to take too much, seek immediate medical attention.
(Click Sinemet Overdose for more information.)