Sinemet Overdose

You should seek immediate medical attention if you think you have overdosed on Sinemet (carbidopa-levodopa). If a person takes too much Sinemet, overdose symptoms could occur and may include vomiting, confusion, and a rapid heart rate. Treatment for a Sinemet overdose may include administering certain medicines, pumping the stomach, or treating symptoms that occur as a result of the overdose.

Sinemet Overdose: An Introduction

Sinemet® (carbidopa-levodopa) is a prescription drug most often used to treat Parkinson's disease. As with any medication, it is possible to take too much Sinemet. The specific effects of a Sinemet overdose can vary, depending on a number of factors, including the Sinemet dosage and whether it was taken with any other medications or substances.
 

Symptoms of a Sinemet Overdose

In cases of an overdose with levodopa (one of the components of Sinemet), the following symptoms were reported:
 
It is expected that Sinemet will cause similar overdose symptoms.
 

Treatment for a Sinemet Overdose

The treatment for a Sinemet overdose may also vary, and there is no known antidote. If the overdose was recent, a healthcare provider may "pump the stomach" or administer certain medications to induce vomiting. Treatment may also involve supportive care, which consists of treating the symptoms that occur as a result of the overdose. For example, supportive treatment options for a Sinemet overdose may include:
 
  • Fluids through an intravenous line (IV)
  • Careful monitoring of the heart, blood pressure, and breathing
  • Other treatments based on the complications that occur.
     
It is important that you seek medical attention immediately if you believe that you may have overdosed on Sinemet.
 
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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