Sinemet Drug Interactions

Sinemet Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Sinemet is combined with any of the drugs listed above.
 
Antipsychotic Medications
Antipsychotic medications can make Sinemet less effective. Check with your healthcare provider before taking these medications together.
 
Blood Pressure Medications
Taking Sinemet and a high blood pressure medication together can increase the risk of low blood pressure (hypotension). Check with your healthcare provider, as you may need a lower dose of your blood pressure medicine.
 
Iron
Iron can decrease the absorption of Sinemet into the body, perhaps making it less effective. Iron products should be taken at least two hours before or after any Sinemet dosage.
 
Isoniazid
Isoniazid can make Sinemet less effective. Check with your healthcare provider before taking these medications together.
 
Metoclopramide (Reglan)
Metoclopramide can make Sinemet less effective. However, metoclopramide may also increase the absorption of Sinemet into the body, which could make it more effective or increase the risk of Sinemet side effects. It is difficult to predict what exactly may happen if these medications are combined. Check with your healthcare provider before taking these medications together.
 
Monoamine Oxidase Inhibitors (MAOIs)
Nonselective MAOIs (isocarboxazid, phenelzine, and tranylcypromine) should not be combined with Sinemet or used within two weeks of using Sinemet. Selective MAOI-B inhibitors (selegiline and rasagiline) can be used with Sinemet, although it may increase the risk of low blood pressure.
The Dirty, Messy Part of BPH

Sinemet Medication Information

Terms of Use
Advertise with Us
Contact Us
About eMedTV
Privacy Policy
Copyright © 2006-2017 Clinaero, Inc.
eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click Terms of Use for more information.