The patents for Sinemet (carbidopa-levodopa) have expired, and generic Sinemet is now available. The FDA has assigned all generic versions of the drug an "AB" rating, meaning they should be equivalent to brand-name Sinemet. However, generic Sinemet may have different inactive ingredients, such as fillers or dyes, from the brand-name medication, which can cause problems for people with allergies or sensitivities.
Generic Sinemet: An OverviewSinemet® (carbidopa-levodopa) is a prescription medication licensed as a Parkinson's disease treatment. It is also approved to treat Parkinson-like symptoms due to other causes.
Brand-name Sinemet is made by Mylan Pharmaceuticals, Inc., for Merck & Co., Inc. However, the patent for the drug has expired, and generic Sinemet is now available.
- Carbidopa-levodopa 10-100 mg
- Carbidopa-levodopa 25-100 mg
- Carbidopa-levodopa 25-250 mg.
- Actavis Elizabeth
- Teva Pharmaceuticals.
Is Carbidopa-Levodopa as Good as Sinemet?All generic medications must undergo certain tests comparing them to brand-name medications. The U.S. Food and Drug Administration (FDA) then looks at these tests to decide if the generics are equivalent to the brand-name medications and assigns a rating to each one. An "AB" rating means that the FDA has determined that a generic medication is equivalent to a brand-name medication. All of the generic Sinemet versions currently available have an "AB" rating, meaning they should be equivalent to Sinemet.
However, generic medications are allowed to have different inactive ingredients from the brand-name medication. This might include fillers, dyes, or other ingredients, which could cause problems for people with allergies or sensitivities.