Sinemet CR Drug Interactions

There are many medications that can potentially interact with Sinemet CR, such as antipsychotic medications, blood pressure medications, and tricyclic antidepressants. Sinemet CR drug interactions may alter the levels of some medicines in your blood, possibly increasing your risk of side effects or other problems. To avoid these interactions, make sure to tell your healthcare provider about any other medications you are taking before starting Sinemet CR.

Sinemet CR Drug Information

Sinemet CR Interactions: An Overview

Sinemet^®CR (carbidopa-levodopa CR) can potentially interact with several different medications. Some of the medicines that may lead to Sinemet CR drug interactions include:

Antipsychotic medications
High blood pressure medications
Iron (including many multivitamins and supplements)
Isoniazid
Metoclopramide (Reglan^®)
Monoamine oxidase inhibitors (MAOIs), including:

Isocarboxazid (Marplan^®)
Phenelzine (Nardil^®)
Rasagiline (Azilect^®)
Selegiline (Eldepryl^®, Emsam^®, Zelapar^®)
Tranylcypromine (Parnate^®)

Phenytoin (Dilantin^®, Phenytek^®)
Tricyclic antidepressants, such as:

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