Sinemet CR Drug Interactions
Phenytoin (Dilantin, Phenytek)
Phenytoin can make Sinemet CR less effective. Check with your healthcare provider before taking these medications together.
There have been reports of occasional problems (such as high blood pressure or involuntary body movements) when Sinemet CR was combined with a tricyclic antidepressant. Check with your healthcare provider before combining Sinemet CR with a tricyclic antidepressant.
Final Thoughts on Sinemet CR Drug InteractionsIt is possible that not all Sinemet CR drug interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about any specific drug interactions that may apply to you.