Side Effects of Procyclidine

Although many side effects of procyclidine are minor, some side effects are more serious and require immediate medical attention. If you develop side effects such as fever, severe constipation, or hallucinations, make sure to notify your healthcare provider right away. Some of the common side effects of procyclidine can include constipation, nausea, and blurred vision. Generally, these types of side effects are easy for you or your healthcare provider to treat.

An Introduction to Procyclidine Side Effects

As with any medicine, procyclidine hydrochloride (Kemadrin®) may cause side effects. If side effects do occur, they are often minor and either require no treatment or are easily treated by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with procyclidine. Your healthcare provider can discuss a more complete list of procyclidine side effects with you.)

Serious Side Effects of Procyclidine

Some side effects with procyclidine are potentially serious and should be reported immediately to your healthcare provider. Although most of these serious side effects are rare, a few may be common, especially with a high procyclidine dosage. These serious side effects of procyclidine include, but are not limited to:
  • Severe constipation (which may be a sign of an intestinal blockage)
  • A rapid heart rate (tachycardia)
  • Confusion
  • Fever, heatstroke, or decreased sweating
  • Glaucoma (an eye condition)
  • Hallucinations
  • Depression
  • Difficulty passing urine
  • Signs of an allergic reaction, including:


    • An unexplained rash
    • Hives
    • Itching
    • Swelling of the mouth or throat
    • Wheezing
    • Difficulty breathing.


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Procyclidine HCL Drug Information

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