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Procyclidine
Procyclidine is a prescription medicine that can help treat the symptoms of Parkinson's disease and movement disorders (extrapyramidal symptoms) that are caused by antipsychotic medications. This medication can also treat excessive drooling caused by Parkinson's disease or antipsychotic medications. It comes in tablet form and is taken three or four times a day. Common side effects include constipation, nausea, and blurred vision.
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Procyclidine hydrochloride (Kemadrin®) is a prescription medication approved for treating the following conditions:
- Parkinson's disease and other similar conditions
- Extrapyramidal symptoms (movement or muscle tension disorders) caused by antipsychotic medications
- Drooling, caused by either Parkinson's disease or antipsychotic medications.
(Click What Is Procyclidine Used For? for more information, including possible off-label uses.)
Common side effects of procyclidine include but are not limited to:
- Constipation
- Nausea
- Dry mouth
- Confusion or memory problems
- Blurred vision (often caused by dry eyes)
- Difficulty passing urine.
(Click Side Effects of Procyclidine to learn more, including potentially serious side effects that you should report immediately to your healthcare provider.)
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD



