Parkinsons Disease Home > Azilect Drug Interactions

There are a number of medications that may interact with Azilect. Drug interactions may occur if Azilect is taken with tricyclic antidepressants, stimulants, certain antibiotics, and other monoamine oxidase inhibitors. Azilect drug interactions could increase your risk of developing dangerous side effects, such as high blood pressure and seizures, or increase the level of Azilect in your blood.

Azilect Drug Interactions: An Overview

Azilect® (rasagiline mesylate) can potentially interact with many medicines. Because there are so many Azilect drug interactions that can be dangerous, it is important to check with your healthcare provider before taking any medication, whether prescription or over-the-counter.
Make sure to tell all your healthcare providers (including dentists and surgeons) that you are taking Azilect. Some of the medicines that may lead to Azilect drug interactions include:
  • Cough, cold, and allergy products, such as:


  • Other monoamine oxidase inhibitors (MAOIs), such as:
    • Dopamine
    • Ephedrine
    • Epinephrine (Adrenalin®, EpiPen®)
    • Isometheptene (Duradrin®, Midrin®, Migquin®, Migratine®, Migrazone®, Migrin-A®)
    • Levonordefrin (Carbocaine with Neo-Cobefrin®)
    • Midodrine (Orvaten®, ProAmatine®)
    • Norepinephrine (Levophed®)
  • Stimulants, such as:
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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