Lodosyn Dosage

Your healthcare provider will recommend an appropriate Lodosyn dosage based on several factors, including your current dose of levodopa and other carbidopa products, other medicines you are taking, existing medical conditions you have, and how you respond to Lodosyn. Dosing will vary from person to person. Generally, the maximum carbidopa dose (from all sources) is 200 mg per day.

 

Lodosyn Dosage: An Introduction

The dose of Lodosyn® (carbidopa) that your healthcare provider recommends will vary, depending on a number of factors, including:
 
  • Your current dose of levodopa and other carbidopa products
  • How you respond to Lodosyn
  • Other medications you are taking
  • Other medical conditions you may have.
     
As is always the case, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
 

Lodosyn Dosing for Parkinson's Disease

Lodosyn is always used in combination with levodopa products (Sinemet®, Sinemet® CR, Parcopa®, Stalevo®), as it has no activity against Parkinson's disease when used alone. While most people take carbidopa as a carbidopa-levodopa combination product, some people will need to add Lodosyn to achieve the right balance of carbidopa and levodopa.
 
Most people need at least 70 to 100 mg of carbidopa a day (from all sources) in order to avoid severe nausea and vomiting due to levodopa. Doses that provide less than 70 mg of carbidopa per day are very likely to cause severe nausea and vomiting.
 
In general, the maximum carbidopa dose (from all sources) is 200 mg per day, as higher doses have not been thoroughly studied.
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;