What Is Bromocriptine Used For?
Bromocriptine for Type 2 DiabetesType 2 diabetes is the most common type of diabetes (see Diabetes Types). It is also sometimes called adult-onset diabetes or non-insulin-dependent diabetes. Type 2 diabetes is a condition in which body cells do not respond to insulin as well as they normally should.
As a result, the body cells remove sugar from the bloodstream very well. This is why type 2 diabetics have high blood sugar.
Bromocriptine (in the form of brand-name Cycloset) can be used alone or in combination with other diabetes medication and is the first (and currently only) diabetes medication of its kind.
Bromocriptine is a dopamine receptor agonist, which means that it binds to and stimulates dopamine receptors. Dopamine is a neurotransmitter (a chemical that transmits signals between nerves). Because the symptoms of Parkinson's disease are caused by low dopamine levels in the brain, bromocriptine can help alleviate Parkinson's symptoms by acting like dopamine.
Acromegaly is caused by high levels of growth hormone. Bromocriptine works for acromegaly by decreasing growth hormone production by the pituitary gland. Bromocriptine works for hyperprolactinemia by decreasing prolactin production by the pituitary gland.
It is not entirely clear how bromocriptine works to control blood sugar in people with type 2 diabetes, but it is thought that stimulating dopamine receptors in the brain at certain times of the day "resets" the biological clock and improves metabolism. It is thought that seasonal changes in the metabolism of wild animals are due to similar mechanisms.
Bromocriptine is approved for treating prolactin-secreting tumors (which cause hyperprolactinemia) in children. It is not approved for other uses in children. Discuss the potential risks and benefits of the drug with your child's healthcare provider.