Apokyn Side Effects

Some people may experience side effects while taking Apokyn. Yawning, nausea, and dizziness are among the most common side effects of this medication. In many cases, Apokyn side effects are minor and are typically easy to treat. However, more serious side effects can occur and may require immediate medical attention. Notify your healthcare provider right away if you develop any serious side effects, such as chest pain, an irregular heart rhythm, or depression.

An Introduction to Apokyn Side Effects

As with any medicine, Apokyn® (apomorphine hydrochloride) may cause side effects. However, not everyone who takes the drug will experience side effects. Many people tolerate it relatively well, at least initially. If side effects do occur, they are often minor and either require no treatment or are easily treated by you or your healthcare provider. However, many people will begin to experience significant and sometimes intolerable Apokyn side effects after several years of use.
 
(This article covers many, but not all, of the possible side effects with Apokyn. Your healthcare provider can discuss a more complete list of Apokyn side effects with you.)
 

Common Side Effects of Apokyn

In clinical studies, common side effects of Apokyn included:
 
  • Yawning -- in up to 40 percent of people
  • Sudden, uncontrollable movements (dyskinesias) -- up to 35 percent
  • Drowsiness -- up to 35 percent
  • Nausea and/or vomiting -- up to 30 percent
  • Reactions at the injection site -- up to 26 percent
  • Dizziness -- up to 20 percent
  • Runny nose -- up to 20 percent
  • Swelling or water retention, especially in the hands or feet -- up to 10 percent.
     
Other common Apokyn side effects (occurring in at least 5 percent of people) included:
 

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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