Drug Interactions With Amantadine

More Information on Interactions With Amantadine

The following sections explain in detail the potentially negative interactions that can occur when amantadine is combined with any of the drugs listed above.
Anticholinergic Medications
Combining amantadine with anticholinergic medications can increase the risk of amantadine side effects. Check with your healthcare provider before taking amantadine with any of these medications.
Antipsychotic Medications
Antipsychotic medications can make Parkinson's disease medications (such as amantadine) less effective. This is probably not an issue if you are taking amantadine for the flu or for uses other than Parkinson's. Check with your healthcare provider before taking an antipsychotic medication if you are taking amantadine for Parkinson's disease.
Intranasal Flu Vaccine (FluMist)
Amantadine may decrease the effectiveness of the intranasal flu vaccine. You must stop taking amantadine at least 48 hours before getting the intranasal flu vaccine, and you should not take it for two weeks after the vaccine. This interaction does not apply to the traditional, injected flu vaccine.
Quinine or Quinidine
Quinine and quinidine may increase the level of amantadine in your blood, possibly increasing your risk of side effects. Check with your healthcare provider before combining amantadine with quinine or quinidine.
Check with your healthcare provider before combining a stimulant with amantadine, as dangerous side effects could occur.

Final Thoughts on Drug Interactions With Amantadine

It is possible that not all drug interactions with amantadine were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about the specific drug interactions that may apply to you.
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